Efficacy of Eight Anticoagulant Food Baits in House Mouse (Mus musculus): Comparison of Choice and No-Choice Laboratory Testing Approaches

Efficacy of Eight Anticoagulant Food Baits in House Mouse (Mus musculus): Comparison of Choice and No-Choice Laboratory Testing Approaches

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House mouse (Mus musculus) is a cosmopolitan pest in agricultural facilities, commodity stores and rural and urban environments.It is regularly controlled by anticoagulant-based baits.Since the number of registered active ingredients is limited, the producers are trying to develop new formulations with increased tamper-resistance, Stepping Stones attractiveness and palatability.

Reliable and economical methods for laboratory screening/testing are needed.Therefore, this work compared simple no-choice with more economically demanding choice feeding tests for laboratory evaluation of efficacy of rodenticide anticoagulant-based preparations in wild populations of house mouse.We analyzed mice survival and bait intake of the various rodenticide commercial preparations differing in a toxic active substance (warfarin, bromadiolone, brodifacoum, difethialone) and CHO-LES-TERIN nontoxic food lure components.

In most cases, we found insignificant differences in survival of house mice treated with eight test baits within the no-choice and choice feeding tests.We rejected the tested hypothesis that there would be significant differences in all tested preparations for two different testing approaches.